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Antihistamines As the name indicates, an antihistamine counters the effects of histamine, which is released by the mast cells in the body''s tissues and contributes to allergy symptoms. For many years, antihistamines have proven useful in relieving sneezing and itching in the nose, throat, and eyes and in reducing nasal swelling and drainage. Many people who take antihistamines experience some distressing side effects: drowsiness and loss of alertness and coordination. In children, such reactions can be misinterpreted as behavior problems. During the last few years, however, antihistamines that cause fewer of these side effects have become available by prescription. These new nonsedating antihistamines are as effective as other antihistamines in preventing histamine-induced symptoms, but do so without causing sleepiness.

Feeling fine in general, allergy symptoms improved. C. T. Have been doing a lot better. Lisa L. So far, so good. Andy G. Felt congested, but improved. Richard R. Feeling fine. No problems. Roland H. Feel OK as far as allergies. Angel P. I felt relief after the treatment, and still feeling better. A. V. I feel OK, but have a little congestion. Carlin R. Feel better than before. Art P. Feel good - continue with sinusitis Bob M. Feeling moderate. Gustavo M. Much better. Alejandro M. What Patients Said After More Than Two Months All my symptoms seem to have gone. Margareth Z. For the first time after taking the treatment, I felt like my life was my own. After 20 years I was able to go out in traffic and high winds with little or no bad effects. I could even tolerate gas lawn mowers. I was able to walk around without huffing and puffing. Pain in throat and lungs disappeared. Getting air in lungs.

All of the active B12 group reporting showed reduction in severity of symptoms ranging from 31% to 70%, while the placebo controls reported either no change or a worsening of symptoms. Wilcoxon-Rank of .002 for the end-points of sneezing, nasal congestion and runny nose; and p = .005 for IgE reductions. In 1992, the above mentioned data from 1988 on were presented by Dr. O''Connor to the FDA. The FDA panel acknowledged the safety of the treatment. The panel seemed to be in agreement that the statistics indicated a significant reduction in IgE and that a quantitative drop in symptoms was demonstrated. In 1992, Belen Anibarro, MD, studied five children with asthma with metabisulfite intolerance confirmed by oral challenge testing. The test was repeated after premedication with 1.5 mg of oral cyanocobalamin. In four of the five patients treated, bronchospasm did not develop in the second metabisulfite challenge.6

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